Kidney Preservation Market Summary
The size of the global kidney preservation market was evaluated at USD 62.3 million in 2024 and is expected to increase at a compound annual growth rate (CAGR) of 7.1% from 2025 to 2030, reaching USD 93.7 million. The growing incidence of end-stage renal disease (ESRD) and chronic kidney disease (CKD), the growing need for organ transplantation, and developments in preservation technologies are some of the reasons propelling the market's expansion.
Key Market Trends & Insights
- The kidney preservation market in North America dominated the overall global market and accounted for a 37.3% revenue share in 2024.
- The kidney preservation market in the U.S. represented an important percentage of North America's kidney preservation industry in 2024.
- By preservation solution, the University of Wisconsin (UW) solution segment accounted for the largest market share of 75.3% in 2024.
- By technique, the Normothermic Machine Perfusion (NMP) segment accounted for the largest revenue share in 2024.
- By donor type, the living donors segment accounted for the largest revenue share in 2024.
Market Size & Forecast
- 2024 Market SizeUSD 62.3 Million
- 2030 Projected Market SizeUSD 93.7 Million
- CAGR (2025-2030)7.1%
- North AmericaLargest market in 2024
- Asia PacificFastest growing market
The need for efficient preservation techniques is being fueled by the rising number of patients awaiting kidney transplants. The frequency of kidney illness increases with age, creating a larger pool of possible transplant patients, which is further fueled by the world's aging population. The World Health Organization (WHO) projects that by 2030, there will be around 1.4 billion elderly people worldwide, up from 1.1 billion in 2023.
By increasing the donor pool and the volume of transplant procedures performed worldwide, the increased awareness of kidney donation and transplantation is having a major impact on the preservation of kidney transplant organs. Increased awareness of the significance and safety of live and deceased kidney donation has been facilitated by public health campaigns, media outreach, and nonprofit campaigning. For example, a new program called "Make Your Mark," which aims to save lives in the UK, was introduced in January 2024. Supported by Kidney Research UK, the campaign sought to increase public awareness of the advantages of living kidney donation and inspire more individuals to think about making a donation. The initiative sought to address the lack of accessible kidneys, as there are currently over 7,000 individuals in the UK waiting for a kidney transplant. We anticipate that such measures will increase the quantity of kidney donations over the projected period. In response, hospitals and transplant facilities are implementing more dependable and cutting-edge preservation methods that guarantee effective organ viability during storage and transportation.
The growing number of people with end-stage renal disease (ESRD) and chronic kidney disease (CKD) around the world, along with the rising need for kidney transplants because they offer better survival rates and quality of life than long-term dialysis, are other reasons for the focus on preserving kidney transplant organs. About 815,000 Americans suffer from renal failure, out of an estimated 35.5 million who have kidney disease, according to the American renal Fund. Dialysis is being used by around 555,000 Americans. Furthermore, more than one in seven (14%) of American adults today suffer from kidney disease, a condition whose prevalence is rising. Similarly, more patients and healthcare systems are choosing kidney transplantation as a result of improvements in immunosuppressive treatments and surgical techniques that have made the process more successful and feasible.
The table below shows the cumulative annual kidney transplants in the U.S. from 2018 to 2024
Technological developments and increased investment in creating cutting-edge kidney preservation technologies are also driving the landscape of kidney transplant organ preservation. To promote next-generation kidney preservation technologies, the National Kidney Foundation (NKF) Innovation Fund made an investment in NorthernLight, a medical device startup, in February 2025. By improving preservation methods, this investment seeks to improve kidney transplantation results. The method developed by NorthernLight may make more kidneys available for transplantation. The NKF Innovation Fund encourages creative approaches to enhance kidney transplantation and health. Therefore, it is anticipated that the convergence of technology, clinical utility, and financial support would stimulate market innovation and thereby propel market expansion.
Market Concentration & Characteristics
There is a noticeable industry concentration in the kidney preservation sector. Because chronic renal illness is becoming more common, there is a growing need for organ transplants, which is driving the market. Developments in preservation methods, such as normothermic and hypothermic machine perfusion, also impact the market.
The growing need for better transplant results and longer organ viability has spurred tremendous innovation in the kidney preservation sector. The industry, which has historically relied on static cold storage, is moving toward more sophisticated techniques, including normothermic and hypothermic machine perfusion. By providing dynamic preservation environments that more closely resemble physiological circumstances, these technologies greatly improve post-transplant results and graft function. For example, Paragonix Technologies reported in January 2025 the first-ever in-human usage of their KidneyVault renal perfusion system (approved by the FDA in October 2024), a technology for preserving kidney transplants. The goal of the system is to lower the chance of delayed transplant function and enhance kidney preservation. The KidneyVault technology has demonstrated encouraging outcomes in preserving kidney function during preservation, the company claims.
The necessity to develop worldwide market reach and consolidate technological capabilities has led to a substantial amount of mergers and acquisitions (M&A) activity in the kidney preservation business. Major players are purchasing companies with exclusive preservation techniques to strengthen their R&D pipelines and address the increasing demand for viable donor kidneys. For example, Getinge stated in August 2024 that it will acquire Paragonix to address urgent demands in solid organ transplantation and greatly expand its worldwide healthcare offering. The goal of this calculated action is to increase access to Paragonix's cutting-edge technologies for organ preservation. We anticipate that the integration of blood perfusion and organ confinement technologies will stimulate innovation, thereby changing market norms and enhancing patient outcomes globally.
In the kidney preservation sector, regulations are essential because they have a significant influence on product development, clinical application, and market uptake. The regulatory oversight from agencies such as the FDA, EMA, and regional bodies is stringent owing to the industry’s reliance on biologically sensitive solutions and advanced preservation technologies. Moreover, compliance with Good Manufacturing Practices (GMP), ISO certifications, and post-market surveillance protocols adds to operational expenses, significantly affecting smaller players. However, regulatory clarity can enhance innovation by establishing safety benchmarks.
In the kidney preservation industry, the threat of substitutes comes primarily from alternative organ preservation and transplant techniques, which could diminish reliance on traditional static cold storage (SCS) and hypothermic machine perfusion (HMP) methods. One new option is normothermic machine perfusion (NMP), which works like the body's normal conditions and allows for longer preservation, better evaluation of how healthy the organ is, and possibly better results after the transplant. Additionally, advancements in regenerative medicine, such as bioengineered kidneys and xenotransplantation (e.g., genetically modified pig kidneys), can present long-term substitute threats. Although these alternatives are currently in experimental or early clinical phases, they could significantly reduce the demand for conventional kidney preservation solutions.
The kidney preservation industry is undergoing significant regional expansion, driven by rising incidences of end-stage renal disease (ESRD), growing organ transplant programs, and advancements in preservation technologies. Moreover, increasing awareness about kidney transplantation and organ donation in emerging regions, owing to government-backed healthcare reforms and improved transplant logistics, is significantly driving market expansion. Additionally, regional partnerships and the entry of global players into these markets enhance access to advanced preservation solutions.
Report Coverage & Deliverables
The PDF report & online dashboard will help you understand
- Competitive benchmarking
- Historical data & forecasts
- Company revenue shares
- Regional opportunities
- Latest trends & dynamics
Preservation Solution Insights
The University of Wisconsin (UW) solution segment accounted for the largest market share of 75.3% in 2024, owing to its proven efficacy in maintaining organ viability during storage and transportation. The solution is made up of special ingredients like antioxidants, energy sources, and ions that don't pass through cell membranes, which work together to reduce cell damage and keep the organ functioning well while it's being preserved. The solution's widespread adoption is also driven by its compatibility with a range of storage and transportation protocols, making it a versatile and reliable choice for kidney preservation.
The Institut Georges Lopez-1 (IGL-1) Solution is anticipated to experience significant growth in the market due to its superior preservation capabilities and increasing adoption by transplant centers. The solution has been shown to reduce ischemia-reperfusion injury and improve graft function in kidney transplantation. The solution's ability to minimize cellular edema and maintain cellular homeostasis contributes to its growing popularity. Thus, as transplant centers increasingly prioritize optimal organ preservation, we expect the demand for the IGL-1 Solution to rise.
Technique Insights
Normothermic Machine Perfusion (NMP) accounted for the largest revenue share in 2024. It is expected to witness the fastest growth owing to its ability to preserve kidneys at normal body temperature, thereby reducing ischemia-reperfusion injury. NMP allows assessing kidney function and viability before transplantation, enabling better decision-making. As a result, NMP is expected to witness the fastest growth, driven by its potential to improve kidney transplant outcomes and increase the availability of donor kidneys. The increasing adoption of NMP can significantly contribute to the kidney preservation and transplant sector, leading to better patient outcomes and improved graft survival rates.
The Static Cold Storage (SCS) segment is also expected to grow significantly due to its simplicity and cost-effectiveness. SCS involves cooling the kidney to a temperature of around 4°C, which slows down metabolic processes, reducing the demand for oxygen and nutrients. This technique has been widely adopted due to its ease of use and minimal requirement for specialized equipment. Moreover, using SCS allows for a longer storage period, which makes it easier to transport kidneys over long distances and increases the demand for kidney preservation.
Donor Type Insights
The living donors segment accounted for the largest revenue share in 2024, owing to the increasing number of living donor kidney transplants, which have become a preferred treatment option for patients with end-stage renal disease (ESRD). The advantages of living donor kidney transplants, such as better graft survival rates and reduced waiting times, have contributed to their growing popularity. Moreover, advancements in surgical techniques and immunosuppressive therapies have made living donor kidney transplants a safer and more effective option. The increasing demand for kidney transplants, coupled with the shortage of deceased donor kidneys, has further driven the growth of living donor kidney transplants.
Donation after Circulatory Death (DCD) is expected to witness the fastest growth in the donor type segment, owing to increasing awareness about DCD and its benefits, such as increased organ availability. DCD donors, also known as non-heart-beating donors, are individuals who have suffered cardiac arrest and are declared dead based on circulatory criteria rather than brain death. The increasing acceptance of DCD kidneys is boosting this segment's growth because they offer another option for kidney transplants, helping to solve the problem of not having enough available organs.
End Use Insights
The transplant centers/hospitals segment accounted for the largest revenue share, 43.5%, in 2024. This can be attributed to the complexity and specialized care required for kidney transplantation procedures. These centers have the necessary infrastructure, including trained personnel and equipment, to handle the complications of organ preservation and transplantation. The expertise and resources available at these centers enable them to effectively utilize kidney preservation technologies, thereby driving their dominance in the market.
The Organ Procurement Organizations (OPOs) segment is expected to witness the fastest growth owing to the increasing demand for organ transplants and the critical role OPOs play in organ donation. OPOs are responsible for coordinating organ donation, ensuring the quality of donated organs, and allocating them to transplant centers. The growing shortage of available kidneys for transplantation has led to an increased focus on optimizing organ procurement and preservation processes. Thus, OPOs are investing in advanced kidney preservation technologies to improve organ viability and increase transplant success rates, thereby fueling the segment's growth.
Regional Insights
The North America kidney preservation market dominated the overall global market and accounted for 37.3% of the revenue share in 2024. The kidney preservation market in North America is driven by a combination of robust organ transplantation infrastructure, rising incidences of end-stage renal disease (ESRD), and a well-established reimbursement landscape. The region benefits from advanced healthcare systems that heavily invest in organ transplant research and innovative preservation technologies, such as hypothermic machine perfusion and normothermic perfusion, further fueling market growth.
U.S. Kidney Preservation Market Trends
The kidney preservation market in the U.S. represented an important percentage of North America's kidney preservation industry in 2024. This can be attributed to the high incidence of end-stage renal disease (ESRD) and a significant rise in kidney transplant procedures across the country. The U.S. healthcare ecosystem, supported by strong transplant networks such as UNOS, has been instrumental in streamlining donor-recipient matching and enhancing organ utilization rates. Regulatory backing from the FDA has further enabled quicker adoption of innovative devices and solutions in clinical practice.
Europe Kidney Preservation Market Trends
The European market for kidney preservation is driven by the increasing prevalence of end-stage renal disease and a rising effort to enhance organ transplantation outcomes. Moreover, the aging population in the region is expected to increase the overall demand for kidney transplantation, thereby fueling market growth. Collaborative initiatives like the Consortium on Organ Preservation in Europe (COPE) are also playing a crucial role in developing and trialing advanced preservation strategies, demonstrating improved organ function and survival rates.
The UK kidney preservation market is witnessing significant growth, owing to the increased demand for transplants and significant technological innovations. Moreover, the high prevalence of diseases such as chronic kidney disease is further increasing the demand for kidney preservation in the country. For instance, according to the NHS England, among adults aged 35 and over, 78% had normal kidney function while 22% had chronic kidney disease (CKD), with a higher prevalence among women (24%) than men (20%); 11% had severe CKD (stages 3-5).
The kidney preservation market in Germany is experiencing notable growth, driven by an increasing demand for organ transplants and advancements in preservation technologies. Government initiatives aimed at increasing organ donation rates and the country's emphasis on healthcare innovation are expected to enhance the adoption of advanced preservation solutions in academic and clinical settings.
Asia Pacific Kidney Preservation Market Trends
The kidney preservation market in the Asia Pacific region is driven by rising incidences of end-stage renal disease (ESRD), expanding transplantation programs, and the increasing adoption of advanced preservation technologies. The region's healthcare infrastructure is evolving, with countries investing in modernizing transplant facilities and training programs to enhance organ donation and transplantation rates. Additionally, the continued funding and new policies aimed at improving transplant results and tackling the rising number of kidney disease cases are likely to boost market growth in the coming years.
The kidney preservation market in Japan is poised for rapid growth, driven by advancements in preservation technologies and increasing demand for organ transplants owing to the rising burden of kidney disease. Over the forecast period, we expect the country's aging population to further increase the demand for kidney transplantation. For instance, the number of elderly people in Japan surged to 36.25 million, accounting for a record high 29.3 percent of the population, according to the figures released by the Ministry of Internal Affairs and Communications.
The kidney preservation market in China is driven by the country’s expanding organ transplantation programs and government-led reforms aimed at increasing donor availability. The establishment of the China Organ Transplant Response System (COTRS) has streamlined donor allocation, improving organ utilization efficiency. Rising incidences of chronic kidney disease and a growing elderly population have further increased the demand for kidney transplants, driving investment in preservation technologies.
The kidney preservation market in India is driven by the rising incidence of chronic kidney disease and expanding transplant programs. Moreover, India’s heavy burden of diabetic nephropathy and hypertension drives a growing demand for kidney transplants, pushing investment in preservation technologies. Moreover, increasing government focus on improving rural healthcare infrastructure is expanding access to transplant services beyond urban centers.
Latin America Kidney Preservation Market Trends
Increased organ transplant procedures and advancements in preservation technologies drive the Latin American kidney preservation industry. Countries such as Brazil are at the forefront, with a significant number of transplantation centers and a growing adoption of machine perfusion methods. However, the region faces challenges including disparities in healthcare infrastructure, limited access to advanced preservation technologies in rural areas, and the need for standardized protocols across countries. Addressing these issues through regional collaborations and investments in healthcare infrastructure is critical to improving kidney preservation and transplantation outcomes in Latin America.
Brazil’s kidney preservation market is driven by the country’s efficient organ procurement and allocation network, led by state-run transplant coordination centers, significantly boosting the utilization of preserved kidneys. The country is also witnessing a rising burden of end-stage renal disease linked to widespread diabetes and hypertension, further intensifying the need for reliable kidney preservation.
Middle East and Africa Kidney Preservation Market Trends
The kidney preservation market in the MEA is witnessing significant growth, driven by diverse regional dynamics and healthcare advancements. In the Middle East, there are significant investments in transplantation infrastructure, driven by rising incidences of chronic diseases such as diabetes and cardiovascular conditions. Similarly, in Africa, there is a significant increase in transplantation activities, supported by international collaborations and efforts to improve healthcare systems.
The kidney preservation market in Saudi Arabia is anticipated to expand in the forecast period. This can be attributed to the government-backed healthcare expansion and targeted reforms in the transplant sector. The Ministry of Health’s Vision 2030 initiative prioritizes organ transplantation as part of broader healthcare modernization, resulting in increased funding for transplant centers and preservation technology. Moreover, the rise in lifestyle-related kidney diseases, particularly diabetic nephropathy, is pushing demand for reliable preservation techniques to ensure successful transplantation outcomes.
Key Kidney Preservation Company Insights
The competitive scenario in the kidney preservation market is highly competitive, with several market players competing to enhance their market positions. The major companies are undertaking various organic and inorganic strategies, such as new product development, collaborations, acquisitions, mergers, and regional expansion, to serve the unmet needs of their customers.
Key Kidney Preservation Companies
The following are the leading companies in the kidney preservation market. These companies collectively hold the largest market share and dictate industry trends.
- TransMedics Inc.
- XVIVO
- Bridge to Life Ltd.
- Paragonix Technologies Inc.
- OrganOx Limited
- Organ Recovery Systems
- Institut Georges Lopez (IGL)
- Preservation Solutions, Inc.
- Dr. Franz Köhler Chemie GmbH
- Essential Pharmaceuticals LLC
Recent Developments
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In October 2024, Paragonix Technologies received FDA 510(k) clearance for its KidneyVault Portable Renal Perfusion System, a device designed to preserve kidneys for transplantation. The system aims to improve kidney preservation and transplantation outcomes. The clearance enables the use of the KidneyVault system in clinical settings.
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In July 2023, Oxford-based medical device company Organox raised USD 33 million to transform organ transplantation practices by improving organ preservation and increasing transplant success rates. The funding will help Organox commercialize its technology and expand its team.
Kidney Preservation Market Report Scope
|
Report Attribute |
Details |
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Market size value in 2025 |
USD 66.6 million |
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Revenue forecast in 2030 |
USD 93.7 million |
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Growth rate |
CAGR of 7.1% from 2025 to 2030 |
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Actual data |
2018-2024 |
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Forecast period |
2025-2030 |
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Quantitative units |
Revenue in USD million/billion and CAGR from 2025 to 2030 |
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Report coverage |
Revenue forecast, company ranking, competitive landscape, growth factors, and trends |
|
Segments covered |
Solution, technique, donor type, end use, region |
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Regional scope |
North America; Europe; Asia Pacific; Latin America; MEA |
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Country scope |
U.S.; Canada; Mexico; UK; Germany; France; Italy; Spain; Denmark; Sweden; Norway; Japan; China; India; Australia; Thailand; South Korea; Brazil; Argentina; South Africa; Saudi Arabia; UAE; Kuwait. |
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Key companies profiled |
TransMedics Inc.; XVIVO; Bridge to Life Ltd.; Paragonix Technologies Inc.; OrganOx Limited; Organ Recovery Systems; Institut Georges Lopez (IGL); Preservation Solutions, Inc.; Dr. Franz Köhler Chemie GmbH; Essential Pharmaceuticals LLC |
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Customization scope |
The purchase includes free report customization, equivalent to up to 8 analysts' working days. Changes or additions to the scope of the country, region, and segment are possible. |
|
Pricing and purchase options |
Avail yourself of customized purchase options to meet your exact research needs. Explore purchase options |
Global Kidney Preservation Market Report Segmentation
This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2018 to 2030. For the purpose of this study, MIR has segmented the global kidney preservation market report on the basis of preservation solution, technique, donor type, end use, and region
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Preservation Solution Outlook (Revenue, USD Million, 2018-2030)
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University of Wisconsin (UW)
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Histidin-Tryptophan-Ketoglutarate (HTK) Solution
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Celsior Solution
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Hypertonic Citrate Adenine (HC-A) Solution
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Institute Georges Lopez (IGL-1) Solution
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Others
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Technique Outlook (Revenue, USD Million, 2018-2030)
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Static Cold Storage
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Hypothermic Machine Perfusion
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Normothermic Machine Perfusion
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Other
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Donor Type Outlook (Revenue, USD Million, 2018-2030)
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Standard Criteria Donor (SCD)
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Expanded Criteria Donor (ECD)
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Donation after Brain Death (DBD)
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Donation after Circulatory Death (DCD)
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Living Donor
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End Use Outlook (Revenue, USD Million, 2018-2030)
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Transplant Centers/Hospitals
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Organ Procurement Organizations (OPOs)
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Others
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Region Outlook (Revenue, USD Million, 2018-2030)
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North America
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U.S.
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Canada
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Mexico
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Europe
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UK
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Germany
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France
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Italy
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Spain
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Denmark
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Sweden
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Norway
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Asia Pacific
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Japan
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China
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India
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Australia
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South Korea
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Thailand
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Latin America
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Brazil
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Argentina
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Middle East & Africa
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South Africa
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Saudi Arabia
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UAE
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Kuwait
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