U.S. Oncology Information Systems Market Report (2025–2035): Industry Trends, Product Innovations, Segment Analysis, and Forecasts by Application and End-Use
Published Date: April - 2025 | Publisher: Market Insights Research | No of Pages: 240 | Industry: Healthcare | Format: Report available in PDF / Excel Format
View Details Buy Now 2999 Download Sample Ask for Discount Request CustomizationU.S. Oncology Information Systems Market Report (2025–2035)Industry Trends, Product Innovations, Segment Analysis, and Forecasts by Application and End-Use
U.S. Oncology Information Systems Market Size and Trends
The U.S. oncology information systems (OIS) market is projected to reach approximately USD 970 million in 2025 and is anticipated to grow to over USD 1.95 billion by 2035, expanding at a compound annual growth rate (CAGR) of 7.4%.
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This growth trajectory is strongly influenced by the rising incidence of cancer, increasing healthcare digitization, and the growing need for comprehensive data management and clinical support tools in oncology care.
As cancer remains one of the leading causes of morbidity and mortality in the U.S., demand for innovative healthcare IT platforms capable of managing complex oncology workflows is intensifying. According to the American Cancer Society, new cancer cases in the U.S. are projected to surpass 2.1 million annually by 2025. These trends underscore the urgent need for real-time, data-driven systems that support oncologists in diagnosis, treatment planning, and patient monitoring.
Oncology information systems are gaining widespread traction due to their ability to streamline treatment protocols, consolidate patient records, enhance multi-disciplinary coordination, and deliver analytics that support clinical decisions. Hospitals, specialty clinics, and research centers are integrating OIS platforms to optimize operational efficiency and personalize patient care pathways. These systems are designed with advanced modules including radiation therapy management, chemotherapy tracking, and survivorship documentation—components essential to comprehensive cancer care.
The growing influence of artificial intelligence (AI) in healthcare is also transforming OIS capabilities. AI-powered tools can extract and analyze unstructured clinical data from EHRs, pathology reports, and radiology notes, enabling oncologists to gain deeper insights into treatment effectiveness and patient progress. For example, in late 2024, Ontada (a subsidiary of McKesson) expanded its collaboration with Microsoft Azure OpenAI to automate the interpretation of oncology datasets, facilitating faster decision-making and better alignment with precision medicine goals.
Moreover, increased R&D funding and innovation are fueling product development in this sector. Leading industry players are introducing OIS platforms with enhanced interoperability, mobile accessibility, and predictive analytics. Simultaneously, non-profit organizations like the American Brachytherapy Society continue to support research, professional education, and awareness programs that are shaping the future of oncology technology.
As healthcare providers in the U.S. embrace value-based care, the need for systems that integrate seamlessly with electronic medical records (EMRs), track patient outcomes, and comply with evolving regulatory standards is intensifying. This macro-shift in healthcare delivery is expected to be a key accelerator for OIS market growth through 2035.
Market Characteristics and Competitive Landscape
The U.S. oncology information systems market is moderately fragmented, characterized by a healthy mix of established players and emerging innovators. The competitive landscape is shaped by a continuous influx of technological advancements, strategic partnerships, and regulatory support aimed at expanding digital healthcare capabilities.
The industry is experiencing consistent growth in R&D investment, with companies actively developing sophisticated treatment planning tools that enhance clinical accuracy and patient outcomes. For instance, in 2022, Elekta introduced Elekta Esprit, a next-generation radiosurgery platform designed to deliver hyper-targeted treatment while preserving cognitive functions. Innovations like these are raising the bar for precision oncology and expanding the utility of OIS platforms beyond standard scheduling and documentation.
Mergers and acquisitions are also influencing the market, with several companies seeking to strengthen their technological capabilities and extend their reach across healthcare ecosystems. A notable example includes the 2022 collaboration between RaySearch Laboratories and GE Healthcare to develop advanced simulation tools for radiation therapy, integrating cutting-edge imaging with OIS functionality.
Regulatory agencies in the U.S. have played a pivotal role in supporting digital transformation within oncology care. The Office of the National Coordinator for Health Information Technology (ONC) enforces interoperability standards that are critical to OIS deployment. These regulations ensure secure data exchange, patient privacy under HIPAA, and enable providers to deliver coordinated, high-quality care.
Regional expansion remains steady as providers seek to extend cancer services into underserved areas and improve access to digital oncology tools. A recent milestone occurred in March 2025, when Trial Library and the American Oncology Network (AON) announced a partnership aimed at increasing access to clinical trials for patients across diverse communities. Such collaborations are vital in enhancing equitable care and furthering adoption of OIS technologies.
As the industry evolves, oncology information systems are becoming central to patient engagement, clinical collaboration, and population health management in oncology. The next phase of market growth will likely be driven by AI integration, cloud-based platform scalability, and a deeper alignment with personalized medicine initiatives.
Report Scope
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Parameter |
Details |
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Report Title |
U.S. Oncology Information Systems (OIS) Market Report (2025–2035) |
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Forecast Period |
2025 to 2035 |
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Base Year for Estimation |
2024 |
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Historical Data |
2019 to 2023 |
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Estimated Market Size (2025) |
USD 970 Million |
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Projected Market Size (2035) |
USD 1.95 Billion |
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CAGR (2026–2035) |
7.4% |
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Geographic Scope |
United States |
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Segments Covered |
Products & Services, Application, End-Use |
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Data Sources |
National Cancer Institute, CDC, Industry Journals, Vendor Interviews |
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Analysis Tools Used |
SWOT, PESTLE, Market Forecast Models, Competitive Benchmarking |
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Objective |
To provide detailed insights into trends, drivers, innovations, and key players |
What are the growth opportunities in this market?
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Products and Services Insights
In 2025, the software segment continued to dominate the U.S. oncology information systems market, capturing a substantial share of approximately 74%. The strength of this segment is anchored in the ability of OIS software to bridge the gap between healthcare providers, oncology specialists, and diagnostic centers by enabling seamless information exchange, real-time treatment monitoring, and enhanced clinical collaboration. These platforms offer oncology-specific electronic medical records (EMRs), treatment planning modules, patient scheduling, and compliance tracking—all integrated to streamline cancer care workflows.
Leading players such as Varian (a Siemens Healthineers company), Flatiron Health, and Elekta are at the forefront of innovation, continuously evolving their platforms with AI-powered analytics, mobile-accessible dashboards, and cloud-based interoperability. As cancer treatment becomes increasingly multidisciplinary and personalized, demand for intelligent software that can harmonize diverse data sources and support evidence-based decision-making is rapidly growing.
Meanwhile, the professional services segment is forecast to grow at a robust pace through 2035, driven by the increasing complexity of system integration and the shortage of in-house expertise in healthcare institutions. Hospitals and oncology centers are turning to third-party providers for consulting, implementation, and technical support. Key players such as eviCore Healthcare, Asclepius Consulting, and Elekta offer tailored services, including clinical informatics, workflow optimization, and long-term platform maintenance to ensure high system uptime and regulatory compliance.
Application Insights
Medical oncology remained the dominant application area in 2025, accounting for nearly 61% of the U.S. OIS market. This segment supports systemic therapies such as chemotherapy, immunotherapy, hormone therapy, and biologics, all of which require detailed patient monitoring, toxicity management, and dosage tracking. With the ongoing evolution of targeted and precision therapies, OIS platforms are increasingly integrated with genomic data and clinical trial registries, enabling oncologists to deliver more individualized treatment plans.
The surgical oncology segment is poised to experience accelerated growth over the forecast period. Modern surgical oncology is no longer limited to tumor removal; it often incorporates advanced interventions such as cytoreductive surgery, isolated limb perfusion, and robot-assisted procedures. These treatments demand meticulous coordination across oncology teams, where OIS tools facilitate pre-operative planning, intra-operative data access, and post-operative follow-up tracking. The rise in complex multimodal cancer treatments is creating new opportunities for OIS platforms tailored to surgical environments.
End Use Insights
Hospitals and diagnostic imaging centers led the market in 2025, securing nearly 47% of total revenue share. These institutions are investing heavily in digital oncology platforms to optimize workflows, reduce treatment errors, and curb operational inefficiencies. By integrating OIS with existing electronic health records (EHRs), hospitals are achieving higher levels of interoperability, which allows providers to access critical information—such as imaging reports, lab results, and treatment timelines—across multidisciplinary teams.
The fastest-growing segment is projected to be ablation care centers and standalone cancer care clinics, which are rapidly expanding their infrastructure and service lines. This growth is largely driven by increased demand for localized and outpatient-based cancer care services. In November 2024, UT Southwestern Medical Center announced a USD 177 million expansion of its radiation oncology unit in Fort Worth, featuring MRI-guided precision radiotherapy. Similarly, in February 2025, Johns Hopkins Medicine expanded its surgical oncology network across the Greater Washington Area. Such expansions not only enhance access but also reinforce the adoption of scalable and cloud-based OIS platforms in these facilities.
Key U.S. Oncology Information Systems Companies Insights
Market-leading OIS providers in the U.S. are increasingly leveraging partnerships, AI technology integration, and R&D investments to strengthen their product portfolios and expand their market footprint. Their focus is shifting toward creating unified oncology ecosystems—combining imaging, diagnostics, treatment planning, and patient engagement under one digital roof.
Key Players in the U.S. Oncology Information Systems Market
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Varian Medical Systems, Inc. (Siemens Healthineers)
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Flatiron Health (Roche Holding AG)
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Cerner Corporation (Oracle Health)
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McKesson Corporation (Ontada)
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Accuray Incorporated
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Koninklijke Philips N.V.
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IBM Watson Health
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ViewRay Inc.
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Epic Systems Corporation
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Carestream Health
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Myriad Genetics, Inc.
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PathomIQ
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Recent Developments
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February 2025 – Myriad Genetics partnered with PATHOMIQ to license its AI platform for prostate cancer diagnostics. The collaboration will lead to the release of a new AI-driven clinical decision support tool, enhancing diagnostic accuracy and enabling more personalized treatment strategies by extracting meaningful patterns from pathology data.
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October 2023 – mTuitive introduced mTuitive Insight, a groundbreaking oncology informatics platform designed to standardize and structure cancer pathology data. The platform supports improved collaboration among oncologists, pathologists, and data scientists by enhancing AI utilization in cancer data aggregation and analysis.
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June 2022 – Accuray Incorporated formed a strategic alliance with Limbus AI Inc. to combine its adaptive radiotherapy solutions with Limbus’s AI-driven auto-contouring technology. This integration aims to reduce treatment planning time and improve precision in radiotherapy, representing a significant step toward fully automated cancer treatment workflows.
U.S. Oncology Information Systems Market Segmentation
By Product & Services
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Software
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Patient Information Systems
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Treatment Planning Systems
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Decision Support & Analytics Tools
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Professional Services
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Consulting & Implementation
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System Integration
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Support & Maintenance
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By Application
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Medical Oncology
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Surgical Oncology
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Radiation Oncology
By End-Use
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Hospitals & Diagnostic Imaging Centers
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Cancer Care Centers
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Ablation Centers
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Academic & Research Institutes
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